What is NAD+?

NAD+, or Nicotinamide Adenine Dinucleotide, is a vital coenzyme found in all living cells. It plays a central role in redox reactions, shuttling electrons between molecules in metabolic pathways like glycolysis and the citric acid cycle.

This 500mg preparation is paired with a 10ml reconstitution solution, allowing researchers to prepare the compound for precise experimental protocols.

Research Significance

In laboratory investigations, NAD+ is studied for its influence on mitochondrial function, oxidative stress response, and cellular signaling. Its involvement in the activation of sirtuins links it to research on aging, DNA repair, and metabolic regulation.

Scientists often evaluate NAD+ levels as a biomarker for cellular health and resilience against environmental stressors.

Mechanistic Overview

NAD+ serves as an electron carrier in catabolic reactions, cycling between oxidized (NAD+) and reduced (NADH) forms. It also functions as a substrate for enzymes such as PARPs and sirtuins, which regulate genomic stability and cellular stress adaptation.

These pathways have become a focus in experimental models of neurodegeneration, metabolic disorders, and muscle performance.

Potential Research Areas

• Mitochondrial bioenergetics
• Oxidative stress and antioxidant defense
• Sirtuin activation pathways
• DNA repair mechanisms
• Aging and cellular longevity studies
• Exercise physiology and recovery

Chemical Data

Chemical Formula: C21H27N7O14P2
Molecular Weight: ~663.43 g/mol
Form: Lyophilized powder with supplied 10ml reconstitution solution

This formulation is designed for controlled dilution and accurate measurement in experimental environments.

Preparation & Storage

Reconstitute NAD+ using the provided 10ml solution according to laboratory specifications. Store lyophilized form at −20°C, away from light and moisture. After reconstitution, refrigerate at 2–8°C and use within recommended timelines. Avoid multiple freeze–thaw cycles.

For Research Use Only

NAD+ 500mg 10ml is intended solely for scientific investigation by qualified professionals. Not for human or veterinary use.

• NAD+ – Wikipedia
• Sirtuins – Wikipedia
• PARPs – Wikipedia